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USG Partners

The achievement of our ambitious goals and implementation of the GHI principles are only possible through the consolidated and coordinated efforts of all the USG agencies working in partnership with the global TB community to combat TB worldwide. The United States Agency for International Development (USAID) is the lead USG agency in international TB control.

USAID works closely with the Office of the Global AIDS Coordinator (OGAC) at the Department of State; OGAC is the lead for the USG response to TB-HIV co-infection as part of PEPFAR.

A key partner in the USAID response and the PEPFAR program is the U.S. Centers for Disease Control and Prevention (CDC), an agency under Department of Health and Human Services (HHS). CDC leads domestic USG TB control efforts and provides critical technical support to international partners on epidemiology and surveillance (including drug-resistant TB), laboratory strengthening, and clinical/operational research that evaluates promising diagnostic and treatment strategies, and informs the efficient use of new approaches to TB care. CDC also funds the TB Clinical Trials Consortium and the TB Epidemiologic Studies Consortium to fill current TB knowledge gaps in TB diagnostics, TB treatment regimens, case detection, and monitoring.

Finally, the National Institutes of Health (NIH) leads the way in improving the biomedical understanding of TB and conducts basic, applied, and clinical research on both drug-sensitive and drug-resistant TB and is heavily involved in the discovery and early development of new drugs, vaccines and diagnostics. All of these agencies are active members of the Stop TB Partnership.

Agency/Initiative Role in International TB Control
USAID Supports implementation and scale-up of all components of the Stop TB Strategy through bilateral programs in 40 countries. Works in partnership with national TB control programs. Supports programmatically relevant operations research and late stage clinical trials.
OGAC Provides support for services to persons co-infected with TB-HIV in PEPFAR countries. Examples include integration of TB and HIV services, HIV testing for TB patients, TB screening and testing of persons with HIV/AIDS, surveillance and laboratory strengthening. OGAC coordinates the USG agencies involved in PEPFAR (HHS, USAID, Department of Labor, Department of Commerce and Peace Corps, coordinated by OGAC).
HHS/CDC Provides critical technical support to international partners on epidemiology and surveillance (including drug-resistant TB), laboratory strengthening, and clinical/operational research that evaluates promising diagnostic and treatment strategies, and informs the efficient use of new approaches to TB care. Funds the TB Clinical Trials Consortium and the TB Epidemiologic Studies Consortium to fill current TB knowledge gaps in TB diagnostics, TB treatment regimens, case detection, and monitoring.
NIH Supports domestic and international biomedical research, including fundamental basic research; studies of pathology, epidemiology, and transmission of TB; studies to characterize drug resistance; research on basic, clinical and behavioral aspects of TB-HIV co-infection; identification, pre-clinical development, and clinical evaluation of new drugs, diagnostics, and vaccines; and research training, infrastructure, and capacity-building in resource-constrained countries.


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