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Zambia

Image of a regional map of Africa, with Zambia highlighted.

 

Tuberculosis (TB) continues to be a major health threat in Zambia and is ranked among the 10 top causes of morbidity and mortality. Zambia has one of the highest incidence rates of TB per capita in the world. The sputum-smear positive (SS+) case notification rate in Zambia is 193 cases per 100,000 population, more than three times the global average of 61 cases per 100,000 population. It also has the 10th highest incidence rate in the world. With strong government commitment and an assured supply of anti-TB drugs through the Global TB Drug Facility, Zambia has achieved 100 percent DOTS (the internationally recommended strategy for TB control) coverage and about 74 percent case detection for all forms of TB. The treatment success rate has also continued to rise since 2003 and is at the World Health Organization (WHO) target of 85 percent. Unfortunately, the TB-HIV/AIDS co-infection rate is high in the country, and HIV is a major contributor to increasing numbers of TB cases. The DOTS case detection of SS+ TB was only 58 percent in 2007, still below WHO’s target of 70 percent.

Zambia’s National TB Strategic Plan for 2006–2010 identified the treatment of TB as a specific objective for the reduction of the socioeconomic impact of HIV/AIDS in the country. Seventy percent of all new TB patients in Zambia are co-infected with HIV, and Zambia has the seventh highest rate for prevalence of co-infection rate in the world. The estimated HIV prevalence rate of 14.3 percent in the adult population has made TB treatment difficult and has strained already limited financial and human resources.1 Multidrug-resistant (MDR) TB seems to be a minor problem so far, as there were an estimated 577 new MDR-TB among SS+ cases, although only 26 cases were confirmed in 2007. , As of March 2009, there are no reports of extensively drugresistant (XDR) TB. However, the upsurge of MDR-TB and XDR-TB in the sub- Saharan African region and the lack of compliance to treatment by 3 percent of the TB patients on treatment may lead to a higher incidence of drug-resistant TB.2

USAID Approach and Key Activities

Chart with the following information: Country Population: 11,922,000, Estimated number of new TB cases: 60,337, Estimated TB incidence (all cases per 100,000 pop): 506, DOTS population coverage (%): 100, Rate of new sputum smear-positive (SS+) cases (per 100,000 pop): 193, DOTS case detection rate (new SS+,%): 58, DOTS treatment success rate in 2006 (new SS+,%): 85, Estimated adult TB cases HIV+(%): 70, New TB cases multidrug-resistant (%): 1.8. All data are for 2007 except where otherwise noted. WHO Global TB Report 2009.

The USAID TB program in Zambia began in fiscal year (FY) 2005, with a budget of $1 million, which supported the initial assessment of Zambia’s National TB Control Program (NTCP). In FY 2008, USAID funding for TB programs was $3.1 million, and USAID has continued to support the NTCP in the implementation of the National TB Strategic Plan. USAID, through the Tuberculosis Control Assistance Program (TB CAP), currently supports TB control activities in Northern, Central, Copperbelt, North-Western, and Luapula provinces, covering five of the nine Zambian provinces. In line with the Stop TB Strategy, the National Health Strategic Plan, and the National TB Strategic Plan, TB CAP aims to ensure that these provinces meet global targets for case detection and treatment success rates. USAID supports activities in the following areas:

  • Strengthening and expanding quality DOTS services through improved laboratory case detection and treatment, and monitoring and evaluation of DOTS programs
  • Standardizing case management training of health care workers with WHOapproved training manuals, supporting supervision, and revising manuals and guidelines
  • Improving collaboration between TB and HIV/AIDS programs at the provincial and district levels
  • Expanding laboratory external quality assurance (EQA) activities to strengthen the laboratory system and identify and support laboratory needs
  • Supporting the Ministry of Health (MOH) to achieve optimal community participation in TB control
  • Increasing community mobilization and involvement in TB and TB-HIV/AIDS care and developing information, education, and communication activities and materials for TB and TB-HIV/AIDS
  • Expanding the involvement of all providers in TB control to include TB-HIV/AIDS in workplace programs and publicprivate mix DOTS
  • Developing policies and guidelines for managing MDR-TB, building capacity to conduct drug susceptibility testing, and conducting drug resistance surveys to find out the actual burden of MDR-TB

USAID Program Achievements

Through TB CAP, USAID has made the following contributions to TB control:

  • Trained 314 health care workers in various TB control concepts, including provider-initiated HIV counseling and testing and community-based TB support concepts
  • Trained and employed seven microscopists for Luapula province and eight microscopists for North-Western province (areas most in need of laboratory support), which contributed to improvements in the percentage of correct diagnoses of SS+ TB in Luapula province (an increase from 81.2 percent in 2007 to 98 percent in 2008) and in North-Western province (an increase from 73.5 percent in 2007 to 92 percent in 2008)
  • Procured laboratory supplies and supported laboratory personnel to increase laboratory capacity, aiding in 94 percent of U.S. Government (USG)-supported laboratories were able to report correct results for TB microscopy more than 95 percent of the time in FY 2008
  • Supported EQA visits conducted by the provincial laboratory staff to identify and support laboratory needs
  • Provided technical and financial support for TB-HIV/AIDS activities, enabling 45 percent of all TB patients in the USGsupported treatment centers to be tested for HIV
  • In collaboration with other USG partners, trained an additional 4,681 health care workers in TB-HIV/AIDS and procured needed commodities, such as protective equipment, microscopes, and laboratory reagents

Case Detection and Treatment Success Rates Under DOTS

Chart measuring the DOTS detection rate and DOTS treatment success rate by year from 2003 to 2007.

Note: DOTS treatment success rate for 2007 will be reported in the WHO Report 2010.
Source: Global Tuberculosis Control WHO Report 2009

Partnerships

USAID support to the NTCP is provided through TB CAP, under the direction of the KNCV Tuberculosis Foundation. TB CAP partners include the Japan Anti-Tuberculosis Association, Family Health International, WHO, and Management Sciences for Health. Other partners include CARE and JHPIEGO. The U.S. CDC provides support with laboratory capacity building. The Global Fund to Fight AIDS, Tuberculosis and Malaria awarded three principal recipients (the MOH, the Church Health Association of Zambia, and Zambia National AIDS Network) a total of $47.3 million in 2003 in Round 1 and $3.9 million in 2008 in Round 7 to implement TB control activities.


1 Preliminary 2007 Demographic and Health Survey
2 USAID data on default rate

May 2009

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